"There is only one Tree Hill Jamie Scott." - Haley Scott
First off, I love how Haley uses 'one' as a pun. She is saying that Tree hill, her home is one of a kind and at the same time, she is taking the name of the serial itself. Maybe the name originated from here. But when a character takes the name of the serial it means only one thing. It is about to end. And end it did.